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Publications

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Title Investigators Year
Cardiac troponin I tyrosine 26 phosphorylation decreases myofilament Ca2+ sensitivity and accelerates deactivation Hussam E Salhi, Shane D Walton, Nathan C Hassel, Elizabeth A Brundage, Pieter P de Tombe, Paul M L Janssen, Jonathan P Davis, Brandon J Biesiadecki 2014
Chemical exchange saturation transfer MR imaging of articular cartilage glycosaminoglycans at 3 T: Accuracy of B0 Field Inhomogeneity corrections with gradient echo method Wenbo Wei, Guang Jia, David Flanigan, Jinyuan Zhou, Michael V Knopp 2014
Combined troponin I Ser-150 and Ser-23/24 phosphorylation sustains thin filament Ca(2+) sensitivity and accelerates deactivation in an acidic environment Benjamin R Nixon, Shane D Walton, Bo Zhang, Elizabeth A Brundage, Sean C Little, Mark T Ziolo, Jonathan P Davis, Brandon J Biesiadecki 2014
Conformational dynamics of a Y-family DNA polymerase during substrate binding and catalysis as revealed by interdomain Förster resonance energy transfer Brian A Maxwell, Cuiling Xu, Zucai Suo 2014
Conformational dynamics of Thermus aquaticus DNA polymerase I during catalysis Cuiling Xu, Brian A Maxwell, Zucai Suo 2014
Displacements, mean-squared displacements, and codisplacements for the calculation of nonequilibrium properties Mithila V Agnihotri, Si-Han Chen, Corey Beck, Sherwin J Singer 2014
Drug design targeting protein-protein interactions (PPIs) using multiple ligand simultaneous docking (MLSD) and drug repositioning: discovery of raloxifene and bazedoxifene as novel inhibitors of IL-6/GP130 interface Huameng Li, Hui Xiao, Li Lin, David Jou, Vandana Kumari, Jiayuh Lin, Chenglong Li 2014
Dynamic conformational change regulates the protein-DNA recognition: an investigation on binding of a Y-family polymerase to its target DNA Xiakun Chu, Fei Liu, Brian A Maxwell, Yong Wang, Zucai Suo, Haijun Wang, Wei Han, Jin Wang 2014
Gene regulation by substoichiometric heterocomplex formation of undecameric TRAP and trimeric anti-TRAP Elihu C Ihms, Mowei Zhou, Yun Zhang, Ian R Kleckner, Craig A McElroy, Vicki H Wysocki, Paul Gollnick, Mark P Foster 2014
HDAC6 deacetylates and ubiquitinates MSH2 to maintain proper levels of MutSα Mu Zhang, Shengyan Xiang, Heui-Yun Joo, Lei Wang, Kendra A Williams, Wei Liu, Chen Hu, Dan Tong, Joshua Haakenson, Chuangui Wang, Shengping Zhang, Ryan E Pavlovicz, Amanda Jones, Kristina H Schmidt, Jinfu Tang, Huiqin Dong, Bin Shan, Bin Fang, Rangasudhagar Radhakrishnan, Peter M Glazer, Patrick Matthias, John Koomen, Edward Seto, Gerold Bepler, Santo V Nicosia, Jiandong Chen, Chenglong Li, Liya Gu, Guo-Min Li, Wenlong Bai, Hengbin Wang, Xiaohong Zhang 2014
Improving bladder cancer imaging using 3-T functional dynamic contrast-enhanced magnetic resonance imaging Huyen T Nguyen, Kamal S Pohar, Guang Jia, Zarine K Shah, Amir Mortazavi, Debra L Zynger, Lai Wei, Daniel Clark, Xiangyu Yang, Michael V Knopp 2014
Inactivation of sortase A mediated by metal ATCUN complexes Insiya Fidai, Lalintip Hocharoen, Seth Bradford, Christine Wachnowsky, J A Cowan 2014
Insight into the recognition, binding, and reactivity of catalytic metallodrugs targeting stem loop IIb of hepatitis C IRES RNA Seth S Bradford, Martin James Ross, Insiya Fidai, James A Cowan 2014
Lysine methylation is an endogenous post-translational modification of tau protein in human brain and a modulator of aggregation propensity Kristen E Funk, Stefani N Thomas, Kelsey N Schafer, Grace L Cooper, Zhongping Liao, David J Clark, Austin J Yang, Jeff Kuret 2014
Mechanistic investigation of the bypass of a bulky aromatic DNA adduct catalyzed by a Y-family DNA polymerase Varun V Gadkari, E John Tokarsky, Chanchal K Malik, Ashis K Basu, Zucai Suo 2014
Nitric oxide-dependent activation of CaMKII increases diastolic sarcoplasmic reticulum calcium release in cardiac myocytes in response to adrenergic stimulation Jerry Curran, Lifei Tang, Steve R Roof, Sathya Velmurugan, Ashley Millard, Stephen Shonts, Honglan Wang, Demetrio Santiago, Usama Ahmad, Matthew Perryman, Donald M Bers, Peter J Mohler, Mark T Ziolo, Thomas R Shannon 2014
Nucleosomes accelerate transcription factor dissociation Yi Luo, Justin A North, Sean D Rose, Michael G Poirier 2014
Quality Control for RNA-Seq (QuaCRS): An Integrated Quality Control Pipeline Karl W Kroll, Nima E Mokaram, Alexander R Pelletier, David E Frankhouser, Maximillian S Westphal, Paige A Stump, Cameron L Stump, Ralf Bundschuh, James S Blachly, Pearlly Yan 2014
Quantitative models for accelerated protein dissociation from nucleosomal DNA Cai Chen, Ralf Bundschuh 2014
Recent insight into the kinetic mechanisms and conformational dynamics of Y-Family DNA polymerases Brian A Maxwell, Zucai Suo 2014
Receptor interacting protein-2 plays a critical role in human lung epithelial cells survival in response to Fas-induced cell-death Mohd Akhlakur Rahman, Kruthika Sundaram, Srabani Mitra, Mikhail A Gavrilin, Mark D Wewers 2014
Ryanodine receptor phosphorylation by oxidized CaMKII contributes to the cardiotoxic effects of cardiac glycosides Hsiang-Ting Ho, Bin Liu, Jedidiah S Snyder, Qing Lou, Elizabeth A Brundage, Florencia Velez-Cortes, Honglan Wang, Mark T Ziolo, Mark E Anderson, Chandan K Sen, Xander H T Wehrens, Vadim V Fedorov, Brandon J Biesiadecki, Thomas J Hund, Sándor Györke 2014
Single molecule fluorescence methodologies for investigating transcription factor binding kinetics to nucleosomes and DNA Yi Luo, Justin A North, Michael G Poirier 2014
Structure and mechanism of action of tau aggregation inhibitors Katryna Cisek, Grace L Cooper, Carol J Huseby, Jeff Kuret 2014
Understanding the sequence requirements of protein families: insights from the BioVis 2013 contests William C Ray, R Wolfgang Rumpf, Brandon Sullivan, Nicholas Callahan, Thomas Magliery, Raghu Machiraju, Bang Wong, Martin Krzywinski, Christopher W Bartlett 2014