Li-Chun Tu

Research Description:

Research in Tu lab focuses on chromosome dynamics during various cellular processes, including cell cycle, DNA damage repair, and transcription. What are the mechanisms that govern chromosome location and movement during DNA damage repair? How are human chromosomes organized to express genes necessary for cell- and tissue-specific functions? We employ interdisciplinary techniques super-resolution CRISPR-based microscopy, biophysical analysis, and biological tools, to tackle fundamental questions in living cells.