Jennifer Ottesen

Research Description:

Research in the Ottesen laboratory utilizes peptide and protein chemistry to address biological problems. The Ottesen group is developing improved techniques for solid phase chemical ligation, which allows the rapid recombination of peptide elements into larger macromolecules. They also employ expressed protein ligation, in which synthetic polypeptides and recombinant protein elements can be chemoselectively linked together. This allows the power of synthetic techniques to be applied to large proteins.