Publications | Biophysics Graduate Program

[1]	Mu Zhang, Shengyan Xiang, Heui-Yun Joo, Lei Wang, Kendra A Williams, Wei Liu, Chen Hu, Dan Tong, Joshua Haakenson, Chuangui Wang, Shengping Zhang, Ryan E Pavlovicz, Amanda Jones, Kristina H Schmidt, Jinfu Tang, Huiqin Dong, Bin Shan, Bin Fang, Rangasudhagar Radhakrishnan, Peter M Glazer, Patrick Matthias, John Koomen, Edward Seto, Gerold Bepler, Santo V Nicosia, Jiandong Chen, Chenglong Li, Liya Gu, Guo-Min Li, Wenlong Bai, Hengbin Wang, and Xiaohong Zhang "HDAC6 Deacetylates and Ubiquitinates MSH2 to Maintain Proper Levels of MutSα." Mol. Cell 55, 31-46 (2014).
[2]	Huameng Li, Hui Xiao, Li Lin, David Jou, Vandana Kumari, Jiayuh Lin, and Chenglong Li "Drug design targeting protein-protein interactions PPIs using multiple ligand simultaneous docking MLSD and drug repositioning: discovery of raloxifene and bazedoxifene as novel inhibitors of IL-6/GP130 interface." J. Med. Chem. 57, 632-41 (2014).
[3]	Bitna Yi, Sihui Long, Tatiana F González-Cestari, Brandon J Henderson, Ryan E Pavlovicz, Karl Werbovetz, Chenglong Li, and Dennis B McKay "Discovery of benzamide analogs as negative allosteric modulators of human neuronal nicotinic receptors: pharmacophore modeling and structure-activity relationship studies." Bioorg. Med. Chem. 21, 4730-43 (2013).
[4]	Patrick C Still, Bitna Yi, Tatiana F González-Cestari, Li Pan, Ryan E Pavlovicz, Hee-Byung Chai, Tran Ngoc Ninh, Chenglong Li, Djaja Djendoel Soejarto, Dennis B McKay, and A Douglas Kinghorn "Alkaloids from Microcos paniculata with cytotoxic and nicotinic receptor antagonistic activities." J. Nat. Prod. 76, 243-9 (2013).
[5]	Ming-Jie Liu, Shengying Bao, Marina Gálvez-Peralta, Charlie J Pyle, Andrew C Rudawsky, Ryan E Pavlovicz, David W Killilea, Chenglong Li, Daniel W Nebert, Mark D Wewers, and Daren L Knoell "ZIP8 regulates host defense through zinc-mediated inhibition of NF-κB." Cell Rep 3, 386-400 (2013).
[6]	Erin N Frey, Ryan E Pavlovicz, Clem John Wegman, Chenglong Li, and Candice C Askwith "Conformational Changes in the Lower Palm Domain of ASIC1a Contribute to Desensitization and RFamide Modulation." PLoS ONE 8, e71733 (2013).
[7]	Olha M Koval, Jedidiah S Snyder, Roseanne M Wolf, Ryan E Pavlovicz, Patric Glynn, Jerry Curran, Nicholas D Leymaster, Wen Dun, Patrick J Wright, Natalia Cardona, Lan Qian, Colleen C Mitchell, Penelope A Boyden, Philip F Binkley, Chenglong Li, Mark E Anderson, Peter J Mohler, and Thomas J Hund "Ca2/calmodulin-dependent protein kinase II-based regulation of voltage-gated Na channel in cardiac disease." Circulation 126, 2084-94 (2012).
[8]	Brandon J Henderson, Tatiana F González-Cestari, Bitna Yi, Ryan E Pavlovicz, R Thomas Boyd, Chenglong Li, Stephen C Bergmeier, and Dennis B McKay "Defining the Putative Inhibitory Site for a Selective Negative Allosteric Modulator of Human α4β2 Neuronal Nicotinic Receptors." ACS Chem Neurosci 3, 682-92 (2012).
[9]	Brandon J Henderson, Daniel J Carper, Tatiana F González-Cestari, Bitna Yi, Kiran Mahasenan, Ryan E Pavlovicz, Martin L Dalefield, Robert S Coleman, Chenglong Li, and Dennis B McKay "Structure-activity relationship studies of sulfonylpiperazine analogues as novel negative allosteric modulators of human neuronal nicotinic receptors." J. Med. Chem. 54, 8681-92 (2011).
[10]	Kiran V Mahasenan, Ryan E Pavlovicz, Brandon J Henderson, Tatiana F González-Cestari, Bitna Yi, Dennis B McKay, and Chenglong Li "Discovery of Novel α4β2 Neuronal Nicotinic Receptor Modulators through Structure-Based Virtual Screening." ACS Med Chem Lett 2, 855-60 (2011).
[11]	Matthew B West, Stephanie Wickham, Leslie M Quinalty, Ryan E Pavlovicz, Chenglong Li, and Marie H Hanigan "Autocatalytic cleavage of human gamma-glutamyl transpeptidase is highly dependent on N-glycosylation at asparagine 95." J. Biol. Chem. 286, 28876-88 (2011).
[12]	Huameng Li, Aiguo Liu, Zhenjiang Zhao, Yufang Xu, Jiayuh Lin, David Jou, and Chenglong Li "Fragment-Based Drug Design and Drug Repositioning Using Multiple Ligand Simultaneous Docking MLSD: Identifying Celecoxib and Template Compounds as Novel Inhibitors of Signal Transducer and Activator of Transcription 3 STAT3." J. Med. Chem. 54, 5592-6 (2011).
[13]	Yan Liu, Aiguo Liu, Huameng Li, Chenglong Li, and Jiayuh Lin "Celecoxib Inhibits Interleukin-6/Interleukin-6 Receptor-Induced JAK2/STAT3 Phosphorylation in Human Hepatocellular Carcinoma Cells." Cancer Prev Res Phila 4, 1296-305 (2011).
[14]	Suzanne Reed, Huameng Li, Chenglong Li, and Jiayuh Lin "Celecoxib inhibits STAT3 phosphorylation and suppresses cell migration and colony forming ability in rhabdomyosarcoma cells." Biochem. Biophys. Res. Commun. 407, 450-5 (2011).
[15]	Ryan E Pavlovicz, Brandon J Henderson, Andrew B Bonnell, R Thomas Boyd, Dennis B McKay, and Chenglong Li "Identification of a negative allosteric site on human α4β2 and α3β4 neuronal nicotinic acetylcholine receptors." PLoS ONE 6, e24949 (2011).
[16]	Huameng Li and Chenglong Li "Multiple ligand simultaneous docking: orchestrated dancing of ligands in binding sites of protein." J Comput Chem 31, 2014-22 (2010).
[17]	Rohit Tiwari, Kiran Mahasenan, Ryan Pavlovicz, Chenglong Li, and Werner Tjarks "Carborane clusters in computational drug design: a comparative docking evaluation using AutoDock, FlexX, Glide, and Surflex." Journal of chemical information and modeling 49, 1581-9 (2009).
[18]	Zhongfa Liu, Shujun Liu, Zhiliang Xie, Ryan E Pavlovicz, Jiejun Wu, Ping Chen, Josephine Aimiuwu, Jiuxia Pang, Deepak Bhasin, Paolo Neviani, James R Fuchs, Christoph Plass, Pui-Kai Li, Chenglong Li, Tim H-M Huang, Lai-Chu Wu, Laura Rush, Hongyan Wang, Danilo Perrotti, Guido Marcucci, and Kenneth K Chan "Modulation of DNA methylation by a sesquiterpene lactone parthenolide." J. Pharmacol. Exp. Ther. 329, 505-14 (2009).
[19]	Tatiana F Gonz�lez-Cestari, Brandon J Henderson, Ryan E Pavlovicz, Susan B McKay, Raed A El-Hajj, Aravinda B Pulipaka, Crina M Orac, Damon D Reed, R Thomas Boyd, Michael X Zhu, Chenglong Li, Stephen C Bergmeier, and Dennis B McKay "Effect of novel negative allosteric modulators of neuronal nicotinic receptors on cells expressing native and recombinant nicotinic receptors implications for drug discovery." J. Pharmacol. Exp. Ther. 328, 504-15 (2009).
[20]	Zhongfa Liu, Zhiliang Xie, William Jones, Ryan E Pavlovicz, Shujun Liu, Jianhua Yu, Pui-kai Li, Jiayuh Lin, Jame R Fuchs, Guido Marcucci, Chenglong Li, and Kenneth K Chan "Curcumin is a potent DNA hypomethylation agent." Bioorg. Med. Chem. Lett. 19, 706-9 (2009).
[21]	B Fuh, M Sobo, L Cen, D Josiah, B Hutzen, K Cisek, D Bhasin, N Regan, L Lin, C Chan, H Caldas, S DeAngelis, C Li, P-K Li, and J Lin "LLL-3 inhibits STAT3 activity, suppresses glioblastoma cell growth and prolongs survival in a mouse glioblastoma model." Br. J. Cancer 100, 106-12 (2009).
[22]	Deepak Bhasin, Katryna Cisek, Trupti Pandharkar, Nicholas Regan, Chenglong Li, Bulbul Pandit, Jiayuh Lin, and Pui-Kai Li "Design, synthesis, and studies of small molecule STAT3 inhibitors." Bioorg. Med. Chem. Lett. 18, 391-5 (2008).

Publications (co-)authored by Chenglong Li with students in the Biophysics program